Pharmacology 2
Unit 1
1. Pharmacology of drugs acting on cardio vascular system
Introduction to hemodynamic and electrophysiology
Drugs used in congestive heart failure
Anti-hypertensive drugs.
Anti-anginal drugs.
Anti-arrhythmic drugs.
Anti-hyperlipidemic
Unit 2
1. Pharmacology of drugs acting on cardio vascular system
Drug used in the therapy of shock.
Hematinics, coagulants and anticoagulants.
Fibrinolytics and anti-platelet drugs
Plasma volume expanders
2. Pharmacology of drugs acting on urinary system
Diuretics
Anti-diuretics.
Unit 3
3. Autocoids and related drugs
Introduction to autacoids and classification
Histamine, 5-HT and their antagonists.
Prostaglandins, Thromboxanes and Leukotrienes.
Angiotensin, Bradykinin and Substance P. e. Non-steroidal anti-inflammatory agents
Anti-gout drugs
Antirheumatic drugs
Unit 4
5. Pharmacology of drugs acting on endocrine system
Basic concepts in endocrine pharmacology. b. Anterior Pituitary hormones- analogues and their inhibitors.
Thyroid hormones- analogues and their inhibitors.
Hormones regulating plasma calcium level- Parathormone, Calcitonin and Vitamin-D.
Insulin, Oral Hypoglycemic agents and glucagon.
ACTH and corticosteroids.
Unit 5
5. Pharmacology of drugs acting on endocrine system
Androgens and Anabolic steroids.
Estrogens, progesterone and oral contraceptives.
Drugs acting on the uterus.
6. Bioassay
Principles and applications of bioassay.
Types of bioassay
Bioassay of insulin, oxytocin, vasopressin, ACTH,d-tubocurarine,digitalis, histamine and 5-HT