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4th SEMESTER

1 

Pharmaceutical Organic Chemistry III

  1. Discuss the Structure, Synthesis, Chemical Reactions, and Uses of Pyrrole/Furan

  2. Discuss the Structure, Synthesis, Chemical Reactions, and Uses of Pyridine

  3. Structure, Synthesis, Chemical Reactions, and Uses of Quiniline/Isoqunoline

  4. Structure, Synthesis, Chemical Reactions, and Uses of Imidazole.

  5. Organic Chemistry of Indole

  6. Wolff-Kishnner reduction

  7. Backmann Rearrangement Reaction.

  8. Oppenauer Oxidation Reaction

2

Medicinal Chemistry I

  1. Define and give the significance of ionization and partition coefficient.

  2. Explain the SAR of beta adrenergic blocking agents.

  3. Classify cholinolytic agents with examples.

  4. Write the synthesis and uses of Dicyclomine and Ipratropium bromide.

  5. Write the synthesis and MOA of Ibuprofen and Halothane.

  6. Classify antipsychotics and write SAR of Phenothiazines.

  7. What are Narcotic agonists and antagonists? Explain their pharmacological action.

  8. Give the synthesis and uses of Phenytoin and Chlorpromazine.

3

Physical Pharmaceutics II

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4

Pharmacology I

  1. Describe the three major effector pathways through which G-protein coupled receptors function.

  2. Discuss about pharmacokinetic drug interactions with suitable examples.

  3. Explain in detail about phase-I biotransformation of drugs with examples.

  4. Classify neuromuscular blockers with examples. Write the mechanism of action, adverse effects and therapeutic uses of curare alkaloids.

  5. Mention the mechanism of action and uses of local anesthetic agents.

  6. Write the pharmacological actions of alcohol.

  7. Classify antiParkinson's drugs with examples. Write the mechanism of action and adverse effects of dopamine precursor.

  8. Discuss in detail the pharmacological actions of morphine.

5  

Pharmacognosy I

  1. Write a note on marine drugs.

  2. Elaborate the role of pharmacognosy in traditional medicine.

  3. Write a note on conservation of medicinal plants.

  4. What is hybridization? Write its significance with respect to medicinal plants giving examples.

  5. Write pharmacognosy of cotton.

  6. Write a note on plant derived hallucinogens.

  7. Write a note on proteolytic enzymes.

  8. Write about edible vaccines.

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